Oct 2, 2006 (CIDRAP News) – In a major push to modernize and speed the production of vaccines for pandemic influenza and other emerging threats, the US Food and Drug Administration (FDA) last week issued new guidance on how to safely and effectively develop new cell-based vaccines.The document, released Sep 28, updates 13-year-old guidelines on cell culture manufacturing, currently used to make vaccines for other diseases such as measles, mumps, and polio, according to an FDA press release.The currently used egg-based method of producing influenza vaccines hasn’t changed much in 50 years and is more laborious than cell culture production techniques. To produce a vaccine, the virus strain must be adapted to grow in eggs, and huge quantities of special fertilized eggs must be available.With cell culture technology, manufacturers grow vaccine components in human or animal cells so the viruses don’t need to be adapted. Cells can be frozen and stored for use when needed, allowing production to be quickly ramped up in the event of an emergency.”The advice will assist manufacturers, including those that make influenza vaccine, both to develop new and better vaccines and to boost production capacity, making us better prepared for the threat of a future influenza pandemic and other infectious diseases,” said Jesse Goodman, MD, MPH, in the press release. Goodman directs the FDA Center for Biologics Evaluation and Research.The guidance helps vaccine makers determine the suitability of a cell culture for manufacturing, as well as test and validate the safety and purity of the cells. The document also advises when to test at different stages of production and defines quality-control testing methods for cell substrate and adventitious agents.The US Department of Health and Human Services (HHS) has made cell-based vaccine manufacturing a central focus of its pandemic plan. In May it awarded $1 billion among five companies to develop cell-based technologies for making flu vaccines.In April 2005, HHS awarded Sanofi Pasteur a $97 million contract to develop a cell-based flu vaccine. The company was the first to receive a federal contract for commercial-scale use of new flu vaccine technology.Last week, Sanofi Pasteur announced the launch of the first clinical trial of its first seasonal influenza vaccine made using cell culture technology.See also: May 4 CIDRAP News article “US awards $1 billion for cell-based flu vaccines”Jun 27, 2005, CIDRAP News article “Momentum builds for cell-culture flu vaccines”
After partnership with Jadranka Group, As part of his tourism studies, Bernays entered into his first partnership with the county-level tourist board.Partnerski sporazum između Bernaysa i Turističke zajednice Zagrebačke županije dogovorili su direktorica Turističke zajednice mr. sc. Ružica Rašperić i dr. sc. Damir Jugo, dekan Bernaysa. „Thanks to the newly signed partnership, students have the opportunity to be directly involved in the daily activities of the tourist board, which includes nine cities, two municipalities and one tourist area. During the internship, students will learn about the work and specifics of various jobs within the organization and will have the opportunity, under the mentorship of renowned tourism experts, to participate in the design and implementation of various projects and services aimed at contributing to tourism development in Zagreb County.. “, Said mr. sc. Ruzica Rasperic.Bernays ima jedan od najmodernijih sustava odabira i pohađanja stručne prakse te izuzetno snažan naglasak stavlja upravo na stjecanje praktičnog znanja i iskustava tijekom studiranja. U prilog važnosti stjecanja praktičnog iskustva govori i podaci da će studenti preddiplomskog studija „Menadžment i marketing turističke destinacije“ provoditi maksimalnih 180 sati na terenskoj nastave te 210 sati na stručnoj praksi. „Bernays is the only one in Croatia to have a study related to the management and marketing of a tourist destination and the only one in the region to provide its students with a narrower specialization through the modules Tourist Destination Branding, Destination Policy and Tourist Guidance and Interpretation in Destinations. That is why I am very pleased that the Zagreb County Tourist Board is one of the first communities that, in cooperation with Bernays, decided to create experts for tourism of the future and develop their destination in accordance with new trends, and with the driving force and energy of innovation and creativity of our student and professional team. “, Added Dr. sc. Damir Jugo.Related news: MODEL OF DUAL EDUCATION IN TOURISM: LOŠINJ JADRANKA GROUP BECAME A BERNAYS PARTNER IN THE TOURISM SECTOR
The largest number of samples arrived at the tenth jubilee evaluation of the World of Malvasia, which is traditionally held a month before Vinistra, this year from 17 to 19 April. A total of 627 samples were registered for the informal world championship of the most famous Istrian variety, of which 270 samples of Malvasia from seven countries – 207 samples from Croatia, 37 samples from Italy, 11 samples from Slovenia, nine from Spain, four samples from Greece and one sample each from Portugal and Montenegro.312 samples of other wines, 28 samples of strong alcoholic beverages and 17 samples of oil also arrived at the competition. The evaluation is traditionally held at the Parentium Plava Laguna hotel at a high professional level with the professional support of the Polytechnic of Rijeka, the Agricultural Department of Poreč and the IT support of the e-computing company.”I have been the president of the evaluation committee for five years, and my role is to ensure that the evaluation takes place regularly and at a high professional level, and to encourage judges to recognize excellence. It’s great that I’ve noticed a big increase in recent years in the quality of samples, so this year, between as many as 270 samples, I can already say that there are great wines. “, said Caroline Gilby, Master of Wine, Chair of the World Malvasia Evaluation Committee.The biggest star of this year’s event is the legendary Steven Spurrier, a British wine critic and winemaker, a great lover of Istria and Istrian wines.Steven Spurrier is coming to Istria”The results will be made public as part of this year’s Vinistra, which will be held from 11 to 13 May in the Žatika Hall in Poreč. We expect about 130 exhibitors, most of which are Istrian winemakers. The partner country is Austria, so visitors will have the opportunity to enjoy the excellent wines of Austrian exhibitors. The constant increase in the number of samples of indigenous varieties that arrive for evaluation World of Malvasia, the rising level of quality of these samples and every year some new young winemakers is a confirmation that we are doing a good job and that Istria can stand on equal footing with the world’s most famous wine regions”, Said Nikola Benvenuti, President of Vinistra. Benvenuti was extremely pleased to announce the arrival of the legendary British critic and winemaker Steven Spurrier, a great friend of Istria and Istrian winemakers, the man most deserving of the democratization of the world’s wine regions. After his Paris tasting in 1976, nothing was the same.Symbol of Poreč and IstriaRonald Korotaj, a member of the Management Board of Plava Laguna, pointed out that this hotel has become a true partner of Vinistra over the years, and together they promote authenticity and originality, emphasizing Istrian wines that are best enjoyed where they are made – in Istria and Porec. “The second week in May, the people of Poreč traditionally reserve for Vinistra, which has become one of the symbols of the city and Istria. As a citizen of Poreč, I remember the beginnings of Vinistra, which 25 years ago was a small event, and today has the power of the most important wine event in the region.”, Said Loris Peršurić, Mayor of Poreč.Nenad Velenik, director of the Tourist Board of the city of Poreč, commented on the last tourist year, which was a record with 3,4 million overnight stays, and this year an increase of about one percent is expected. “In Poreč, the emphasis is on the pre and post season, developing facilities and projects that increasingly attract guests at a time of year when the sea and sun are not the primary motive for arrival, and here Vinistra fits perfectly and is definitely the highest quality event in Istria. indoors”, Said the director of the Tourist Board of the city of Porec.</p>
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The Tourist Board of the city of Šibenik presented a new logo / visual identity that will be used with the existing logo of the Tourist Board of Šibenik for promotional purposes, which aims to further highlight two Šibenik cultural and tourist pearls under UNESCO protection, St. Nicholas Fortress and St. Jacob’s Cathedral .Šibenik is the only smaller city in the world that has two monuments under UNESCO protection, and our goal was to visually highlight our cultural wealth and the specificity by which we are unique in the world, said the director of the Tourist Board of Šibenik Dino Karađole.”We use the new visual through all our communication, from emails, memos to all promotional materials, all to highlight our incredible cultural wealth, two UNESCO-protected monuments “Karadjole points out.Thus, the new visual identity is dominated by the orange color, which represents the color of Šibenik, as well as two UNESCO monuments as the main motifs.Director of the Tourist Board of the City of Šibenik Dino Karađole: We are not even at 50% of the tourist potentialThe tourist season in Šibenik, as in most tourist destinations on the Adriatic, is in the black, and as Karađole points out, the tourist potential for today’s growth is huge. “ For now, we can be satisfied, we achieved great growth in May, while in June and July we achieved less than expected, which in my opinion is the result of the World Cup. However, Šibenik is rising from year to year, and we are practically not even at 50% of the tourist potential. We have all the prerequisites for daily quality growth through year-round tourism of a higher category to be a TOP destination. From accommodation facilities, development of congress tourism, two monuments under UNESCO protection, our fortress, Michelin-starred restaurant, two national parks nearby, etc.… Great growth potential in the pre- and post-season is certainly through congress tourism, which grows from year to year. thanks to Solaris, which a few years ago put Šibenik at the very top of congress tourism. Also, the most important thing is that they are guests of higher purchasing power and are looking for interaction with the city of Šibenik as well as additional facilities. “Concludes Karadjole.UNESCO’s protectorate is a huge marketing benefit because it guarantees the visit of a certain category of tourists, but it is also a great obligation to owners, ie users because the sustainability criteria are very high and therefore its value is more significant. Everyone who has this label, whether for tangible, natural or intangible heritage, points it out with pride because they are aware of its significance.The logo was made by “2FG studio” from Šibenik.
Most accommodation units available in the group Resorts and similar facilities for short vacations Domestic tourists spent most nights in the City of Zagreb, and foreign tourists in Dubrovnik Tourists in the age group of 65 and over realized the most overnight stays In the first five months of 2019, 3,6 million tourist arrivals and 9,9 million overnight stays were realized in commercial accommodation facilities, which is an increase in tourist arrivals by 3,9%, but a decrease in overnight stays by 4,0% compared to the same period in 2018. Domestic tourists realized 215 thousand arrivals and 486 thousand overnight stays in May 2019, which is an increase of arrivals by 7,9% and an increase of overnight stays by 10,1% compared to May 2018. Foreign tourists realized 1,4 million arrivals and 4,4 , 2019 million overnight stays in May 2018, which is compared to May 6,2. a decrease in arrivals by 16,7% and a decrease in overnight stays by XNUMX%. In the group Hotels and similar accommodation, more than 77 thousand rooms and suites were available to tourists (which is 31,2% of the total number of available rooms and suites) with more than 162 thousand permanent beds (which is 25,3% of the total number) available permanent beds). The average occupancy of rooms was 57,8%, and permanent beds 52,7%. In May 2019, most tourist nights were spent in hotels, more than 2 million overnight stays, which is 43,2% of the total number of nights spent. Compared to May 2018, the number of tourist arrivals in hotels increased by 4,4%, but the number of overnight stays decreased by 1,7%. Foreign tourists spent the most nights in Dubrovnik, the City of Zagreb, Rovinj – Rovigno, Poreč – Parenzo and Split, which is 34,6% of the total number of nights spent by foreign tourists. In May 2019, there were 249 thousand rooms, apartments and camping places available to tourists with more than 638 thousand permanent beds. Tourists from the United Kingdom realized the most overnight stays, more than 118 thousand, which is 25,8% of the total overnight stays of foreign tourists in Dubrovnik. This is followed by overnight stays of tourists from the USA (13,2%), Germany (7,0%) and France (6,7%). Dubrovnik, the city with the highest number of tourist arrivals and overnight stays Domestic tourists realized the most overnight stays in the City of Zagreb, Rovinj – Rovigno, Opatija, Split, and Dubrovnik, which is 28,0% of the total overnight stays of domestic tourists. In the group Resorts and similar facilities for short vacations, 94 thousand rooms and suites were available to tourists (which is 37,9% of the total number of available rooms and suites) with 246 thousand permanent beds (which is 38,5% of the total number of available permanent bed). An increase in tourist arrivals, and a decrease in overnight stays in the first five months of 2019. Of foreign tourists, most arrivals and overnight stays in May 2019 were realized by tourists from Germany, namely 208 thousand arrivals and 973 thousand overnight stays (15,4% of total foreign arrivals and 21,9% of total foreign tourist nights). Compared to May 2018, tourists from Germany experienced a significant decrease in arrivals and overnight stays (36,5% fewer arrivals and 47,8% fewer overnight stays). This is followed by overnight stays of tourists from Austria (10,8%), the United Kingdom (10,7%), Slovenia (8,3%), the USA (4,4%), Poland (4,2%), France (3,9 , 3,5%) and the Netherlands (2018%). Compared to May XNUMX, tourists from Slovenia, the United Kingdom and the USA recorded an increase in overnight stays, while tourists from Austria, Poland, France and the Netherlands recorded a decrease in overnight stays. Domestic tourists realized the most overnight stays in the age group of 35 to 44 years (19,9% of the total overnight stays of domestic tourists), and then in the age group up to 14 years (18,4% of the total overnight stays of domestic tourists). Foreign tourists realized the highest number of overnight stays in the age group of 65 and over (23,5% of the total overnight stays of foreign tourists), followed by the age group of 55 to 64 (20,1% of the total overnight stays of foreign tourists). Most overnight stays of foreign tourists were realized by tourists from Germany (19,7%), Austria (10,6%), Slovenia (9,7%), the United Kingdom (7,9%), Italy (4,5%) and the USA (4,2%). In May 2019, 1,6 million tourist arrivals and more than 4,9 million overnight stays were realized in commercial accommodation facilities. Compared to May 2018, there was a decrease in tourist arrivals by 4,5% and a decrease in overnight stays by 14,6%, according to data from the Central Bureau of Statistics (CBS). In the first five months of 2019, domestic tourists realized more than 700 thousand arrivals and 1,6 million overnight stays, which is 6,9% more arrivals of domestic tourists and 7,3% more overnight stays than in the same period in 2018. In the first five months of 2019, foreign tourists realized 2,9 million arrivals and 8,3 million overnight stays, which is 3,2% more arrivals of foreign tourists and 5,9% fewer overnight stays compared to the first five months of 2018. In May 2019, Dubrovnik was the city with the highest number of tourist arrivals and overnight stays, 159 thousand tourist arrivals and 471 thousand overnight stays. Compared to May 2018, tourists in Dubrovnik increased their arrivals by 9,7% and the number of overnight stays by 2,3%. In May 2019, tourists in the age group of 65 and over realized the most overnight stays, more than 1 million, which is 21,8% of the total overnight stays. Tourists from Germany realized significantly fewer arrivals and overnight stays, but still the most numerous For the fifth month in a row, the highest number of tourist nights in hotels Photo: Pexels.com / Source: CBS
The head of Korona presented what measures are planned in the near future and called on caterers to constantly communicate their problems and concrete proposals for their elimination to the city authorities so that they can solve them operationally as soon as possible. By the way, Zadar is the first and one of the few cities that completely released entrepreneurs from the obligation to pay for public areas and business premises due to the coronavirus crisis. “The first refers to the implementation of the Decision on exemption from payment of public areas, ie the moratorium for May and possibly June. The second concerns the payment of already contracted public areas from June and July, which will be reduced by the prescribed anti-epidemiological measures, so that caterers will not be able to use them objectively to generate income. Also, advance payments for contracts for the use of public areas for this year that could not be used should be taken into account when calculating financial obligations to the city”, Explained the director of HGK ŽK Zadar Denis Ikić after the meeting. Representatives of Zadar caterers met today in HGK ŽK Zadar with the head of city property Tomislav Koron, and the main topic of conversation was future steps in the preparation and conduct of catering activities in the city. In May, catering facilities will open exclusively on outdoor areas and terraces, but they are still plagued by many doubts and problems. Therefore, they proposed to the city authorities two concrete measures to help caterers. All participants in the meeting agreed that they should work responsibly and come to decisions together that will maximally facilitate the reactivation of the hospitality industry and the city economy as a whole.
3) Vouchers – measures to encourage Croatian tourist spending, for the next season, vouchers, for example, as Slovenia has done. Eg. voucher for free toll for the trip to Dalmatia and back if you have paid accommodation, 50% discount on the ferry and the like. Long-term measures: 2) Funds for recovery and resilience – we suggest that part of the funds go as a grant, and part should certainly be allocated for investments 5) Abolition of 3% consumption tax for caterers and recognition of the cost of representation in 100%, with non-taxable so-called. tip for employees, with a maximum account increase of up to 10%. 4) Abolition of mandatory membership fees in the CNTB – financing primarily from sojourn taxes and reduction of the number of tourist unions and abolition of those that have no purpose. 1) Legal solution or regulation related to the moratorium on loans and leasing to all activities related to tourism – mandatory approval of the moratorium for 12 months (with an additional 6 months for the most vulnerable companies) to all clients who on 31.12.2019. were regular clients, with an interest collection model for the moratorium period that will be adequately divided into three parts – clients, leasing companies and the state. Photo: Pixabay.com Current measures: 2) Extension of measures for “preservation of jobs” – participation in the net salary, with the write-off of payroll taxes, for all whose business can not be opened for objective reasons or has a decline of more than 60%, caused by the COVID 19 crisis. It is necessary to keep in mind activities that according to the NCEA do not belong to the tourism sector, and depend almost exclusively on tourism, such as the event industry, destination retail, rent a car industry and the like. Following the meetings of the UGP at the Ministry of Tourism and Sports with Minister Nikolina Brnjac with other tourism workers, it was agreed that each of the Associations submit initial proposals (short-term and long-term, feasible and concise) and the Voice of Entrepreneurs Association submitted current and long-term measures to the Ministry of Tourism. . 3) Enable online payment by CROcard – this is not possible at the moment, and thus an entire sector of online travel agencies is thrown out of the market system, as well as micro-entrepreneurs, ie small renters. 1) Reduction of VAT on all branches of tourism – hotels, restaurants, travel agencies, charters, rent-a-car, carriers, seasonal craftsmen, event industry, etc. at a single rate of 10% 4) Division of Croatia into Covid – 19 regions – not all regions are equally affected by the corona virus and we believe that it is necessary to divide Croatia into zones. It is necessary to separate heavily infected areas from parts that can live normally, of course with all the prescribed precautions.